Mechanisms and management of asthma exacerbations

Title: Mechanisms and management of asthma exacerbations
Creator: Ramsahai, J. Michael; Hansbro, Philip M.; Wark, Peter A. B.
Relation: American Journal of Respiratory and Critical Care Medicine Vol. 199, Issue 4, p. 423-432
Publisher Link: http://dx.doi.org/10.1164/rccm.201810-1931CI
Publisher: American Thoracic Society
Resource Type: journal article
Date: 2019
Description: Acute asthma remains an important medical emergency, the most frequent cause of acute admissions in children and a major source of morbidity for adults with asthma. In all ages with asthma, the presence of exacerbations is an important defining characteristic of asthma severity. In this review, we assess the epidemiology of acute asthma, the triggers of acute exacerbations, and the mechanisms that underlie these exacerbations. We also assess current treatments that prevent exacerbations, with an emphasis on the role of type 2 airway inflammation in the context of acute exacerbations and the novel treatments that effectively target this. Finally we review current mana ement strate ies of the exacerbations themselves
Subject: asthma; asthma exacerbations; virus-induced asthma exacerbations; management of acute asthma; SDG 3; Sustainable Development Goals
Identifier: http://hdl.handle.net/1959.13/1458887
Identifier: uon:45534
Identifier: ISSN:1073-449X
Language: eng
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